Type 2 & other diabetes

Does computerized cognitive training improve diabetes self-management and cognition? A randomized control trial of middle-aged and older veterans with type 2 diabetes

Diabetes Res Clin PractPublished Randomised controlled trial

Authors' conclusion

The adaptive computerized cognitive training was not substantially better than non-adaptive, but may improve memory. Post-hoc results for the combined arms suggest computer-related activities may improve diabetes self-management and other outcomes for middle-aged and older patients with type 2 diabetes. Practice effects or awareness of being studied cannot be ruled out.

Study context

Population
Veterans without dementia aged 55+ with T2D, Bronx, NY and Ann Arbor, MI90 per arm
Participants
90 vs 90
Comparison
Adaptive vs non-adaptive computerized cognitive training
  • Adaptiven = 90
  • Non-adaptiven = 90reference
Primary endpoint
Diabetes self-management, improvement from baseline in the adaptive arm
Follow-up
6 months post-intervention
Methodological detailstwo-site (Bronx, NY and Ann Arbor, MI)
  • Two-site (Bronx, NY and Ann Arbor, MI)

Primary result

As reported in the abstract

Diabetes self-management
  • Contrary to the hypothesis, adaptive arm did not show more improvement in self-management than non-adaptive (only memory did)
  • Intention-to-treat analysis
  • Linear mixed model analyses

Secondary outcomes

OutcomeP value
MemoryMore improvement in adaptive armP < 0.01

Self-management, arms combined (post-hoc) · six-months post-intervention

Self-management improved
P < 0.001
  • Post-hoc analysis

Other outcomes, arms combined (post-hoc)

Memory, executive functions/attention, prospective memory, diastolic and systolic blood pressure improved
P < 0.05
HbA1c and medication adherence did not improve significantly
  • Post-hoc analysis

Original publication

Does computerized cognitive training improve diabetes self-management and cognition? A randomized control trial of middle-aged and older veterans with type 2 diabetes. Diabetes Res Clin Pract. Published 22 November 2022. doi:10.1016/j.diabres.2022.110149

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