Distribution and determinants of coronary artery calcium score in asymptomatic patients with Type-2 diabetes: The French-CAC100 score
Authors' conclusion
Regardless of the geographic area, patients with T2D share similar risk factors for high CACS. The French-CAC100 score allows the identification of those at higher risk of elevated CACS.
Study context
- Population
- Asymptomatic cardiovascular disease (CVD)-free patients with T2D with coronary artery calcium score (CACS) measured in three centres (two in continental France, one in Reunion Island)
- Participants
- 796 patients3 centres
- Comparison
- French-CAC100 score in continental France vs Reunion Island
- Outcome
- Prediction of CACS ≥ 100 by a derived risk score
Methodological detailsmulticentre, derivation in continental France, validation in Reunion Island
- Multicentre
- Derivation in continental France, validation in Reunion Island
Performance
As reported in the abstract
AUC of French-CAC100 score for CACS ≥ 100
French-CAC100 score < 10: NPV for CACS ≥ 100
90%
French-CAC100 score < 10: NPV for CACS ≥ 400
97%
French-CAC100 score < 10: CT-scans avoided
58%
Further findings
- CACS distributions similar in continental France and Reunion Island
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Distribution and determinants of coronary artery calcium score in asymptomatic patients with Type-2 diabetes: The French-CAC100 score. Diabetes Res Clin Pract. Published 11 August 2023. doi:10.
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