Type 2 & other diabetes

Disability and Quality of Life Measures in older frail and prefrail people with type 2 diabetes. The MIDFRAIL-Study

Diabetes Res Clin PractPublished Secondary analysis of the MIDFRAIL randomised trial

Primary result · Improvement in QOL (EQ-5D-5L)Result — go to the resultOdds ratio 1.75 95 % CI 1.20–2.54

Authors' conclusion

IG has proven to be effective in increasing QOL and avoiding the worsening of QOL and basic ADL.

Study context

Population
Prefrail and frail individuals ≥ 70 years with T2D; mean age 77.83 years, 50.65 % men
Participants
843 participants
Comparison
Multicomponent intervention vs usual care

Primary result

Improvement in QOL (EQ-5D-5L)

Odds ratio

1.75

95 % CI 1.20–2.54

p-value 0.004

IGvs UCG
OR 1.75 (95 % CI 1.20–2.54); p-value 0.004

As reported in the abstract

Further findings

OutcomeOR (95 % CI)P value
Deterioration in Barthel Index (basic ADL)Lower probability of deterioration with IG0.59 (0.37–0.93)0.023
OutcomeOR (95 % CI)P value
Deterioration in QOLLower probability of deterioration with IG0.61 (0.87–0.54)0.006

Adherence needed for benefit

Adherence needed for quality of life (QOL) benefits
≥93 %
Adherence needed for Barthel Index benefits
> 84.38 %

Original publication

Disability and Quality of Life Measures in older frail and prefrail people with type 2 diabetes. The MIDFRAIL-Study. Diabetes Res Clin Pract. Published 27 July 2024. doi:10.1016/j.diabres.2024.111797

Composed by AI from the published abstract and checked against it. How Briefs are made →

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