Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma Is Related to a Poor Outcome: A Comparison Study Using Propensity Score Matching
Main finding · Persistent/recurrent diseaseResult — go to the resultOdds ratio 6.288 95% CI 1.900–20.811Authors' conclusion
This propensity score-matched analysis found that the histologic type of DSV-PTC may increase the risk of persistent/recurrent disease.
Study context
- Population
- Patients with PTC after postoperative RAI therapy35 diffuse sclerosing variant of papillary thyroid carcinoma (DSV-PTC) and 240 classic variant of papillary thyroid carcinoma (CV-PTC) included
- Participants
- 35 vs 105
- Exposure
- DSV-PTC vs CV-PTC
- DSV-PTCn = 35
- CV-PTCn = 105reference
- Outcome
- Persistent/recurrent disease
Methodological detailspropensity score matching (1:3 matching ratio)
- Propensity score matching (1:3 matching ratio)
Main finding
As reported in the abstract
Odds ratio
6.288
95% CI 1.900–20.811
P = 0.003
By group
DSV-PTCvs CV-PTC
OR 6.288 (95% CI 1.900–20.811); P = 0.003
Observational data: associations, not effects.
Further findings
5-year DFS · shorter DFS with DSV-PTC (Kaplan-Meier)
P = 0.001
Original publication
Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma Is Related to a Poor Outcome: A Comparison Study Using Propensity Score Matching. Endocr Pract. Published 9 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →