Dietary interventions for the management of type 2 diabetes mellitus in childhood and adolescence: A systematic review
Authors' conclusion
There is limited evidence and a lack of robust clinical trials to support the effectiveness of dietary interventions for CYP-onset T2DM. With evidence of benefit in adulthood and encouraging initial results in the young, it is imperative that fully powered randomised trials with longer follow-up are undertaken to determine efficacy.
Study context
- Population
- Children and young people under 19 years with T2D; Embase, MEDLINE, CENTRAL, Web of Science and CINAHL searched January 2000 to May 20235 papers
- Comparison
- Dietary interventions for T2D in children and young people
- Outcome
- Glycaemic control as measured by HbA1c
Pooled result
As reported in the abstract
HbA1c with very low energy diets (VLED), 2 interventional studies (n = 28) · 8 weeks
HbA1c reduction with very low energy diets (VLED)
16 mmol/mol
3.6%
Further pooled results
Pharmacotherapy requirement and weight with VLED
- VLED associated with decreased requirement for pharmacotherapy and weight loss
Self-reported dietary strategies (observational studies)
- Most frequent strategies were limiting sweets and increasing fruit/vegetable intake, but efficacy was limited
- Limiting fat intake associated with improved HbA1c in women
Original publication
Dietary interventions for the management of type 2 diabetes mellitus in childhood and adolescence: A systematic review. Diabet Med. Published 9 February 2025. doi:10. 1111/ dme. 70005
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