NIR-II imaging-based detection of early changes in lower limb perfusion in type 2 diabetes patients without peripheral artery disease
Authors' conclusion
NIR-II imaging can effectively detect early perfusion changes in T2D patients, showing great potential for pre-diagnosis of individuals at high risk for PAD.
Study context
- Population
- T2D patients without peripheral artery disease (PAD) undergoing NIR-II imaging with indocyanine green
- Participants
- 120 patients
- Comparison
- Plaque vs non-plaque
- Outcome
- NIR-II parameters for lower limb arterial plaques
Performance
As reported in the abstract
- Six NIR-II parameters (T start, T 1/2, Tmax, Ingress rate, Egress, Egress rate) showed significant differences and diagnostic efficacy between groups
- Independent predictors of lower limb artery plaques: T start, Egress, Egress rate, age and sex
- Nomogram: combined model of NIR-II parameters and clinical characteristics had higher diagnostic efficacy
Original publication
NIR-II imaging-based detection of early changes in lower limb perfusion in type 2 diabetes patients without peripheral artery disease. Diabetes Res Clin Pract. Published 8 February 2025. doi:10.
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