The efficacy of behavioral interventions on cardiovascular risk factors in patients with type 2 diabetes: a systematic review and network meta-analysis of randomized trials
Authors' conclusion
Overall, multicomponent behavioral strategies appear most effective for sustained HbA1c improvement, although stronger evidence is needed for fasting glucose and adiposity outcomes.
Study context
- Population
- Adults with T2D; PubMed, Scopus and Web of Science searched up to March 2025
- Comparison
- Behavioral interventions vs each other and control
- Outcome
- HbA1c
Methodological detailsrandom-effects, frequentist framework, GRADE certainty assessment
- Random-effects
- Frequentist framework
- GRADE certainty assessment
Pooled result
As reported in the abstract
MD, % (95% CI)
SBT0-3 months; moderate-certainty evidence
−0.24(−0.41 to −0.06)
CBT + SBT + MIvs SBT12-36 months
−1.84(−2.04 to −1.63)
Further pooled results
Systolic BP and HDL-C
- Standard behavioral therapy (SBT) reduced systolic blood pressure and increased HDL cholesterol
Fasting blood glucose
- Cognitive behavioral therapy (CBT) combined with SBT or motivational interviewing (MI) showed highest effectiveness; SBT plus control ranked well at 6-12 months
Original publication
The efficacy of behavioral interventions on cardiovascular risk factors in patients with type 2 diabetes: a systematic review and network meta-analysis of randomized trials. Diabetes Res Clin Pract. Published 12 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →