Lipids & metabolic liver disease

Prevalence of fatty liver and diabetes mellitus in patients with fatty pancreas disorder (FPD): A meta-analysis and systematic review

Diabetes Res Clin PractPublished Systematic review and meta-analysis

Authors' conclusion

The strong association between FPD and fatty liver suggests shared metabolic drivers in ectopic fat deposition.

Study context

Population
Patients with fatty pancreas disorder; PubMed, Scopus and Web of Science searched up to May 2026
Participants
6,834 patients19 studies
Comparison
FPD vs non-FPD
  • FPDn = 6,834
Outcome
Prevalence of fatty liver and DM in patients with FPD
Methodological detailsrandom-effects models, subgroup analyses by imaging modality and geographic region
  • Random-effects models
  • Subgroup analyses by imaging modality and geographic region

Pooled result

As reported in the abstract

Pooled prevalence in FPD

Pooled prevalence of fatty liver

59.0 %

95 %CI 51.1–66.6

Pooled prevalence of diabetes mellitus (DM)

20.6 %

95 %CI 15.0–26.8

Further pooled results

OutcomeOR (95% CI)
Fatty liver7.87 (5.09–12.17)
DM3.19 (2.11–4.82)

Prevalence in MRI/MRS studies (subgroup)

%

Fatty liver, MRI/MRS studies
76.5
DM, MRI/MRS studies
27.7

Original publication

Prevalence of fatty liver and diabetes mellitus in patients with fatty pancreas disorder (FPD): A meta-analysis and systematic review. Diabetes Res Clin Pract. Published 10 September 2026. doi:10.1016/j.diabres.2026.113563

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