Diabetic complications and risk of depression and anxiety among adults with type 2 diabetes
Main finding · Depression and/or anxietyResult — go to the resultHazard ratio 1.77 95% CI 1.73–1.80Authors' conclusion
Individuals with type 2 diabetes and diabetic complications are at increased risk of depression and anxiety. This points towards the importance of an increased clinical focus on mental well-being among individuals with type 2 diabetes and complications.
Study context
- Population
- Adults diagnosed with T2D between 1997 and 2017 without a recent history of depression or anxiety
- Participants
- 265,799 adults1,915,390 person-years
- Exposure
- Diabetic complications vs no diabetic complications
- Outcome
- Incident depression and/or anxiety, defined by hospital contacts and prescription-based medication
- Follow-up
- From T2D diagnosis until incident depression or anxiety, emigration, death or 31 December 2018
Main finding
Depression and/or anxiety
Hazard ratio
1.77
95% CI 1.73–1.80
By group
Diabetic complications
3368 per 100,000 person-years
Without
1929 per 100,000 person-years
Diabetic complicationsvs Without
HR 1.77 (95% CI 1.73–1.80)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Depression and/or anxiety by type of diabetic complication
- Strongest association: amputation of lower extremities, HR
- 2.16 (2.01-2.31) (95% CI)
- Weakest association: retinopathy, HR
- 1.13 (1.09-1.17) (95% CI)
- Risk increased for all types of diabetic complications
Original publication
Diabetic complications and risk of depression and anxiety among adults with type 2 diabetes. Diabet Med. Published 29 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →