Risk factors for peripheral artery disease and diabetic peripheral neuropathy among patients with type 2 diabetes
Authors' conclusion
Our study contributed to identifying high-risk individuals and improving lower limb health among diabetic individuals.
Study context
- Population
- Chinese patients with T2D; mean age 63.3 years; data November 1, 2018 to December 31, 2022
- Participants
- 13,315 patients
- Outcome
- Prevalence of PAD (ABI ≤ 0.9) and DPN, and associated risk factors
Main finding
As reported in the abstract
PAD prevalence
4.9 %
Diabetic peripheral neuropathy (DPN) prevalence
43.9 %
Observational data: associations, not effects.
Further findings
Independent risk factors for PAD (multivariate regression)
- Advanced age, smoking, hypertension, coronary heart disease, dyslipidemia, elevated HbA1c and uric acid levels were independent risk factors for PAD
Independent risk factors for DPN (multivariate regression)
- Advanced age, female gender, hypertension, coronary heart disease, elevated total cholesterol, TG, lipoprotein(a), FPG, HbA1c, alkaline phosphatase, cystatin C, albumin-to-creatinine ratio and homocysteine were independent risk factors for DPN
- Apolipoprotein A was a protective factor for DPN
Clustering of risk factors
- Clustering of risk factors was prevalent and associated with higher disease risk
Original publication
Risk factors for peripheral artery disease and diabetic peripheral neuropathy among patients with type 2 diabetes. Diabetes Res Clin Pract. Published 26 December 2023. doi:10.
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