Association between adherence to the EAT ‐Lancet diet and risk of microvascular complications in type 2 diabetes: A cohort study
Main finding · Microvascular complicationsResult — go to the resultHazard ratio 0.76 95% CI 0.64–0.88Authors' conclusion
Our findings demonstrate a significant inverse association between adherence to the EAT-Lancet diet and the risk of microvascular complications in individuals with T2D.
Study context
- Population
- Individuals with T2D free of diabetic microvascular complications (retinopathy, neuropathy, nephropathy) at baseline, UK Biobank1,217 developed complications
- Participants
- 7,525 individuals
- Exposure
- Highest vs lowest adherence to the EAT-Lancet diet index
- Outcome
- Incident diabetic microvascular complications
- Follow-up
- Mean 12.58 years
Methodological detailsUK Biobank cohort, Diet assessed by web-based 24-hour dietary recall; Cox proportional hazard models
- UK Biobank cohort
- Diet assessed by web-based 24-hour dietary recall; Cox proportional hazard models
Main finding
Microvascular complications
Hazard ratio
0.76
95% CI 0.64–0.88
Highest adherencevs Lowest adherence
HR 0.76 (95% CI 0.64–0.88)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Microvascular complications per 1-point increase in EAT-Lancet diet index
- Lower risk of microvascular complications per 1-point increase
- 8%
Incident diabetic retinopathy, neuropathy and nephropathy
- Subtype analyses yielded consistent results
Sensitivity and subgroup analyses
- Findings robust across several sensitivity analyses and nearly all subgroups
Original publication
Association between adherence to the EAT ‐Lancet diet and risk of microvascular complications in type 2 diabetes: A cohort study. Diabetes Obes Metab. Published 23 April 2025. doi:10.
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