Diabetes Complications and Cognitive Function in Young Adults with Youth-Onset Type 1 or Type 2 Diabetes: The SEARCH for Diabetes in Youth Study
Authors' conclusion
These findings highlight shared (PN) and unique factors (hypoglycemia in T1D; SBP in T2D) that could be targeted to potentially mitigate cognitive issues in young people with youth-onset diabetes.
Study context
- Population
- Young adults with youth-onset T1D or T2D, SEARCH for Diabetes in Youth study cohort
- Participants
- 646 vs 165
- Exposure
- Clusters of diabetes complications and clinical factors vs cognitive performance, separately in T1D and T2D
- T1Dn = 646
- T2Dn = 165
- Outcome
- Age-corrected scores for composite:
- Fluid cognition
- Associated cognitive subdomains (NIH Toolbox Cognition Battery)
Methodological detailscluster analysis, three-cluster solution per diabetes type
- Cluster analysis
- Three-cluster solution per diabetes type
Main finding
As reported in the abstract
Age-corrected composite fluid cognition score across clusters
- Average age-corrected composite fluid cognition score differed significantly across clusters in each group
- p<0.001
Observational data: associations, not effects.
Original publication
Diabetes Complications and Cognitive Function in Young Adults with Youth-Onset Type 1 or Type 2 Diabetes: The SEARCH for Diabetes in Youth Study. Pediatr Diabetes. Published 8 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →