Delivery Mode and Neonatal Thyrotropin Levels: Insights From a Systematic Review and Meta-Analysis
Pooled result · Pooled TSH levelsResult — go to the resultHedges' g 0.390Authors' conclusion
The study found that the method of delivery has a significant impact on neonatal TSH levels, especially in umbilical cord blood samples, highlighting the need to consider delivery mode in evaluating neonatal health.
Study context
- Population
- Neonates; studies published up to 2023 (MEDLINE/PubMed, Web of Science, Embase, Scopus, Cochrane Library)18 studies
- Comparison
- Vaginal delivery vs cesarean section
- Outcome
- Neonatal thyroid-stimulating hormone (TSH) levels at birth
- Follow-up
- At birth
Methodological detailsrandom effects model
- Random effects model
Pooled result
Pooled TSH levels
Hedges' g
0.390
P = 0.002
As reported in the abstract
Further pooled results
| Outcome | Hedges' g | P value |
|---|---|---|
| TSH levels, heel blood subgroupNo significant difference | 0.167 | P = 0.111 |
| TSH levels, cord blood subgroup | 0.493 | P = 0.002 |
Original publication
Delivery Mode and Neonatal Thyrotropin Levels: Insights From a Systematic Review and Meta-Analysis. Endocr Pract. Published 13 February 2025. doi:10.
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