Cross‐sectional association of metrics derived from continuous glucose monitoring with cognitive performance in older adults with type 2 diabetes
Authors' conclusion
Hyperglycaemia metrics and TIR derived from CGM are associated with cognitive functions, especially with executive function and working memory, in older adults with T2D.
Study context
- Population
- Outpatients with T2D aged ≥70 years; Continuous glucose monitoring (CGM) for 14 daysanalysed
- Participants
- 100 outpatients
- Outcome
- Association of CGM-derived metrics (mean SG, CV, TIR, TAR, TBR) with cognitive performance (MoCA-J, delayed word recall, digit symbol substitution, letter word fluency, trail-making test (TMT), DSP)
Main finding
As reported in the abstract
Cognitive performance by CGM metrics (multiple regression adjusted for confounders)
- Higher mean sensor glucose (SG) associated with lower performance in MoCA-J and TMT-B
- P < .05
- Higher time above range (TAR) associated with lower performance in TMT-B and DSP-backward
- P < .05
- Higher time in range (TIR) associated with better function in TMT-B and DSP-backward
- P < .05
Observational data: associations, not effects.
Original publication
Cross‐sectional association of metrics derived from continuous glucose monitoring with cognitive performance in older adults with type 2 diabetes. Diabetes Obes Metab. Published 28 September 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →