Cross‐sectional association of continuous glucose monitoring‐derived metrics with cerebral small vessel disease in older adults with type 2 diabetes
Authors' conclusion
The hyperglycaemia metrics and TIR, derived from CGM, were associated with cerebral SVD in older adults with type 2 diabetes.
Study context
- Population
- Older adults (≥70 years) with T2D who underwent 14-day continuous glucose monitoring (CGM)analysed
- Participants
- 80 adults
- Outcome
- Association of CGM-derived metrics with total cerebral small vessel disease (SVD) score (0-4: lacunes, microbleeds, enlarged perivascular spaces, white matter hyperintensities), ordinal logistic regression
Main finding
As reported in the abstract
Total cerebral SVD score
Median small vessel disease (SVD) score (IQR 0-2)
1
Time in range (TIR) (per 10% increase) associated with lower total SVD score, OR
0.73
95% CI 0.56–0.95
Observational data: associations, not effects.
Original publication
Cross‐sectional association of continuous glucose monitoring‐derived metrics with cerebral small vessel disease in older adults with type 2 diabetes. Diabetes Obes Metab. Published 19 May 2024. doi:10.
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