Type 2 & other diabetes

Cost‐utility analysis and drug pricing for tirzepatide for type 2 diabetes in the Chinese market compared with semaglutide

Diabetes Obes MetabPublished Cost-utility analysis

Authors' conclusion

This study shows that, using SEMA as a reference, the annual costs for TIRZ 10 and 15 mg are $1573.00-$1967.16 and $1576.54-$2133.96, respectively, for patients with type 2 diabetes in China.

Study context

Population
Patients with T2D in China; cohort and efficacy data from the SURPASS-2 trial
Comparison
Tirzepatide 5, 10, 15 mg vs semaglutide 1 mg
Outcome
Most matchable price of TIRZ vs SEMA
Methodological detailslifetime simulation, binary search, Chinese healthcare provider's perspective, univariate sensitivity analysis, probabilistic sensitivity analysis, scenario analysis
  • Lifetime simulation
  • Binary search
  • Chinese healthcare provider's perspective
  • Univariate sensitivity analysis
  • Probabilistic sensitivity analysis
  • Scenario analysis

Main finding

As reported in the abstract

Cost range for TIRZ (most matchable price)

Tirzepatide (TIRZ) 5 mg

$1628.61-$1846.23

TIRZ 10 mg

$1738.40-$2140.95

TIRZ 15 mg

$1800.30-$2430.81

Further findings

Quality-adjusted life years · lifetime simulation

OutcomeTIRZ 5 mgTIRZ 10 mgTIRZ 15 mgSEMA 1 mg
Cost range for TIRZ after adjustment in univariate sensitivity analysis$1542.68-$1757.57$1573.00-$1967.16$1576.54-$2133.96— not stated in the abstract

— not stated in the abstract

Cost range for TIRZ after adjustment in univariate sensitivity analysis

Cost intervals validated by probabilistic sensitivity and scenario analyses, except for TIRZ 5 mg

Original publication

Cost‐utility analysis and drug pricing for tirzepatide for type 2 diabetes in the Chinese market compared with semaglutide. Diabetes Obes Metab. Published 13 May 2024. doi:10.1111/dom.15645

Composed by AI from the published abstract and checked against it. How Briefs are made →

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