Continuous glucose monitoring with low-glucose alerts in insulin-treated drivers with diabetes: A randomized crossover study
Authors' conclusion
Low-glucose alerts improved the TBR in drivers with type 1 diabetes and reduced the incidence of low-glucose while driving among all insulin-treated drivers, suggesting that these alerts may ensure the safety of insulin-treated drivers.
Study context
- Population
- Insulin-treated drivers with diabetes driving cars at least thrice weekly, Japan27 completed continuous glucose monitoring (CGM) analysis
- Participants
- 30 participants
- Comparison
- CGM with active low-glucose alerts vs blinded CGM without alerts
- Primary endpoint
- Percentage of TBR (<3.9 mmol/L)
Methodological detailssingle-centre, open-label, 8-week washout
- Single-centre
- Open-label
- 8-week washout
Primary result
As reported in the abstract
TBR (<3.9 mmol/L)
- Time below range (TBR) did not differ between alert and no-alert periods among all participants
Further findings
Incidence of low glucose when driving · significantly lower during alert period
P = 0.041
| Outcome | Difference (%) (95 % CI) | P value |
|---|---|---|
| TBR in participants with T1DSignificantly decreased during alert period | −4.4 (- 8.7, −0.08) | P = 0.047 |
Original publication
Continuous glucose monitoring with low-glucose alerts in insulin-treated drivers with diabetes: A randomized crossover study. Diabetes Res Clin Pract. Published 28 February 2025. doi:10. 1016/ j. diabres. 2025. 112074
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