Diabetes technology

Continuous glucose monitoring with low-glucose alerts in insulin-treated drivers with diabetes: A randomized crossover study

Diabetes Res Clin PractPublished Randomised crossover study

Authors' conclusion

Low-glucose alerts improved the TBR in drivers with type 1 diabetes and reduced the incidence of low-glucose while driving among all insulin-treated drivers, suggesting that these alerts may ensure the safety of insulin-treated drivers.

Study context

Population
Insulin-treated drivers with diabetes driving cars at least thrice weekly, Japan27 completed continuous glucose monitoring (CGM) analysis
Participants
30 participants
Comparison
CGM with active low-glucose alerts vs blinded CGM without alerts
Primary endpoint
Percentage of TBR (<3.9 mmol/L)
Methodological detailssingle-centre, open-label, 8-week washout
  • Single-centre
  • Open-label
  • 8-week washout

Primary result

As reported in the abstract

TBR (<3.9 mmol/L)
  • Time below range (TBR) did not differ between alert and no-alert periods among all participants

Further findings

Incidence of low glucose when driving · significantly lower during alert period

P = 0.041

OutcomeDifference (%) (95 % CI)P value
TBR in participants with T1DSignificantly decreased during alert period−4.4 (- 8.7, −0.08)P = 0.047

Original publication

Continuous glucose monitoring with low-glucose alerts in insulin-treated drivers with diabetes: A randomized crossover study. Diabetes Res Clin Pract. Published 28 February 2025. doi:10.1016/j.diabres.2025.112074

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