Continuous Glucose Monitoring in the Intensive Care Unit: A Multicenter, Retrospective Hospital-Based Analysis
Authors' conclusion
These preliminary findings suggest CGM use does not appear to be significantly affected during critical illness.
Study context
- Population
- ICU patients with COVID-19 in three intensive care units (ICUs); >80% with a history of diabetes, mean age 61 ± 12 years; 82% received corticosteroids, 93% mechanical ventilation, 62% vasopressors
- Participants
- 169 patients6,783 CGM-POC pairs
- Exposure
- Hospital A vs Hospital B vs Hospital C
- Outcome
- CGM accuracy (sensor-meter agreement) and changes during hemodynamic instability
Methodological detailsmulticenter, hybrid protocol combining point-of-care (POC) blood glucose testing with intermittent nonadjunctive continuous glucose monitoring (CGM)
- Multicenter
- Hybrid protocol combining POC blood glucose testing with intermittent nonadjunctive CGM
Main finding
As reported in the abstract
CGM accuracy vs POC during critical illness
Mean absolute relative difference (MARD) in patients on dialysis (higher), linear mixed models (LMM) coefficient
2.39
P = .05
MARD in patients on mechanical ventilation (lower), LMM coefficient
−4.33
P = .05
Pairs within Clarke zones A and B
97.3%
Observational data: associations, not effects.
Further findings
| Outcome | Hospital A | Hospital B | Hospital C |
|---|---|---|---|
| CGM TIR (70-180 mg/dL)Median | 72% (IQR 64.9–81.4) | 70% (IQR 54.0–76.9) | 46% (IQR 26.6–68.5) |
| Time below 70 mg/dL | median <0.1% | median <0.1% | median <0.1% |
Original publication
Continuous Glucose Monitoring in the Intensive Care Unit: A Multicenter, Retrospective Hospital-Based Analysis. J Diabetes Sci Technol. Published 10 June 2025. doi:10.
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