Type 1 diabetes

Continuous Glucose Monitoring in Pediatric Diabetic Ketoacidosis

J Diabetes Sci TechnolPublished Prospective diagnostic accuracy study

Authors' conclusion

Continuous glucose monitoring use in inpatient pediatric DKA treatment was found to be feasible and reliable.

Study context

Population
Children admitted to the paediatric ICU for diabetic ketoacidosis (DKA); mean ± SD age 11.9 ± 4.1 years
Participants
35 children
Comparison
Real-time continuous glucose monitoring (rtCGM) vs point-of-care (POC) capillary and serum glucose
Outcome
Accuracy of rtCGM glucose vs POC capillary and serum glucose during standard DKA treatment, by Clarke Error Grid analysis
Methodological detailssingle-arm, single-centre
  • Single-arm
  • Single-centre

Performance

As reported in the abstract

Clarke Error Grid: matched pairs in clinically acceptable A + B zones

CGM/POC pairs in A + B zones (of 524 matched pairs)

95.4%

CGM/serum glucose pairs in A + B zones (of 91 matched pairs)

95.6%

Secondary outcomes

Mean LOS

Average LOS (mean ± SD)
1.32 ± 0.73 days

Relationship between rtCGM readings and degree of acidosis

Serum bicarbonate level did not appear to affect the accuracy of rtCGM in DKA

Original publication

Continuous Glucose Monitoring in Pediatric Diabetic Ketoacidosis. J Diabetes Sci Technol. Published 23 November 2022. doi:10.1177/19322968221140430

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