Type 1 diabetes

Continuous Glucose Monitoring in Hospitalized Adults With Diabetic Ketoacidosis: A Prospective Open-Label Pilot Study

J Diabetes Sci TechnolPublished Prospective open-label pilot study

Authors' conclusion

Our study indicates that CGM technology is a reliable tool for hospital use during acute insulin treatment and after the resolution of DKA.

Study context

Population
Hospitalised adults with diabetic ketoacidosis (DKA) (T1D n = 24, T2D n = 28); age 49 ± 19 years, admission glucose 503 ± 239.4 mg/dL
Participants
52 adults
Exposure
Real-time continuous glucose monitoring (CGM) vs capillary point-of-care (POC) and basic metabolic panel (BMP) glucose
Outcome
CGM accuracy vs POC: MARD, median ARD
Follow-up
During initial IV insulin period
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Mean absolute relative difference (MARD) vs POC, intravenous (IV) insulin period

17.4% ± 13.2%

Median absolute relative difference (ARD) vs POC, IV insulin period (IQR)

14.2%

6.4, 28

MARD vs POC, after DKA resolution

19.8% ± 18.7%

Median ARD vs POC, after DKA resolution (IQR)

14.3%

7, 26.2

Observational data: associations, not effects.

Further findings

Diabetes Technology Society (DTS) Error Grid: values in zones A+B

During IV insulin treatment
100%
After DKA resolution
95%

CGM accuracy vs BMP glucose: MARD, median ARD

MARD vs BMP, IV insulin treatment
18.5% ± 19.1%
Median ARD vs BMP, IV insulin treatment
12.2% (5.4, 23.8)
MARD vs BMP, after DKA resolution
22.5% ± 24.7%
Median ARD vs BMP, after DKA resolution
15.1% (6.6, 27.6)

Original publication

Continuous Glucose Monitoring in Hospitalized Adults With Diabetic Ketoacidosis: A Prospective Open-Label Pilot Study. J Diabetes Sci Technol. Published 5 February 2025. doi:10.1177/19322968251316887

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