Osteoporosis, bone & mineral

Comparison of Fractures Among Older Adults Who Are Ambulatory vs Those Who Use Wheelchairs in Sweden

JAMA Netw OpenPublished Retrospective cohort study

Authors' conclusion

In this retrospective cohort study of older adults, wheelchair use was associated with a lower risk of fracture than observed in ambulatory controls.

Study context

Population
Adults 65 years or older with a health evaluation at Swedish health care facilities, 2007–2017 (mean [SD] age 83.2 [8.3] years; 60.5% women)
Participants
55,442 vs 55,442
Exposure
Wheelchair users vs matched ambulatory controls
  • Wheelchairn = 55,442
  • Ambulatory controlsn = 55,442reference
Outcome
Incident fracture, injurious falls without fracture, and deaths
Methodological detailspropensity score matched 1:1 using 22 variables, national database
  • Propensity score matched 1:1 using 22 variables
  • National database

Main finding

As reported in the abstract

Fracture
Each group vs ambulatory controlsEstimate (95% CI)
Wheelchair
HR (any fracture) 0.43(0.41–0.44)
Wheelchair
HR (major osteoporotic fracture) 0.32(0.31–0.33)
Wheelchair
HR (hip fracture) 0.30(0.28–0.32)

Observational data: associations, not effects.

Further findings

OutcomeEstimate
Injurious fallsRemained highly similar after adjustmentsunadjusted HR 0.48 (95% CI 0.47–0.50)
DeathHR 1.35 (95% CI 1.33–1.36)

Follow-up duration

Original publication

Comparison of Fractures Among Older Adults Who Are Ambulatory vs Those Who Use Wheelchairs in Sweden. JAMA Netw Open. Published 1 February 2023. doi:10.1001/jamanetworkopen.2022.55645

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