Comparing the glycaemic outcomes between real‐time continuous glucose monitoring ( rt‐CGM ) and intermittently scanned continuous glucose monitoring ( intermittently scanned continuous glucose monitoring (isCGM) ) among adults and children with type 1 diabetes: A systematic review and meta‐analysis of randomized controlled trials
Pooled result · Absolute TIR; HbA1cResult — go to the resultMD +7.0 % 95% CI 5.8%–8.3%Authors' conclusion
This meta-analysis highlights that for people with T1D, rtCGM confers benefits over isCGM primarily related to increased TIR, with improvements in hypo- and hyperglycaemia.
Study context
- Population
- People with T1D of any age and insulin regimen; 354 adults, 92 children and adolescents
- Participants
- 446 people5 randomized controlled trials (RCTs)
- Comparison
- Real-time continuous glucose monitoring (rtCGM) vs isCGM
- Outcome
- Co-primary: HbA1c and TIR 70-180 mg/dL (3.9-10.0 mmol/L)
- Follow-up
- Post-intervention
Methodological detailsrandom-effect meta-analysis, Cochrane RoB2, GRADE, 4 parallel and 1 crossover RCT; 4 with CGM use <8 weeks
- Random-effect meta-analysis
- Cochrane RoB2
- GRADE
- 4 parallel and 1 crossover RCT; 4 with CGM use <8 weeks
Pooled result
Absolute TIR; HbA1c
MD
+7.0 %
95% CI 5.8%–8.3%
P < 0.01
As reported in the abstract
Further pooled results
| Outcome | MD (%) (95% CI) | P value | |
|---|---|---|---|
| Time-below-range <70 mg/dL (3.9 mmol/L) · post-intervention | - 1.7 (−3.0% to −0.4%) | P = 0.03 | |
| −4−202Difference, % (linear scale) |
Original publication
Comparing the glycaemic outcomes between real‐time continuous glucose monitoring ( rt‐CGM ) and intermittently scanned continuous glucose monitoring ( isCGM ) among adults and children with type 1 diabetes: A systematic review and meta‐analysis of randomized controlled trials. Diabet Med. Published 10 January 2024. doi:10.
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