Effect of switching from intermittently scanned to real‐time continuous glucose monitoring on glycaemic outcomes in adults with type 1 diabetes: A real‐world, Canadian retrospective study
Main finding · HbA1c reduction, matched cohortsResult — go to the resultAdjusted mean difference 5 mmol/mol [0.5%]Authors' conclusion
This real-world analysis of adults with T1D showed that switching from isCGM to rtCGM use led to significant improvements in HbA1c and CGM metrics.
Study context
- Population
- Adults with T1D in a Canadian speciality care population, LMC Diabetes Registry, January 1, 2018–July 31, 2023; switch cohort mean age 43 years, diabetes duration 20.9 years, baseline HbA1c 67 mmol/mol [8.2%]136 in real-time CGM (rtCGM) switch cohort
- Participants
- 84 vs 84
- Exposure
- Switch from intermittently scanned continuous glucose monitoring (isCGM) to rtCGM vs continued isCGM
- rtCGM switchn = 84
- isCGMn = 84reference
- Outcome
- Change in HbA1c
- Follow-up
- 6-12 months
Methodological detailsreal-world, registry-based (Canadian LMC Diabetes Registry), propensity score-matched comparison
- Real-world
- Registry-based (Canadian LMC Diabetes Registry)
- Propensity score-matched comparison
Main finding
HbA1c reduction, matched cohorts · 6-12-month follow-up
Adjusted mean difference
5 mmol/mol [0.5%]
P = 0.002
As reported in the abstract
Observational data: associations, not effects.
Further findings
HbA1c change from baseline, full rtCGM switch cohort · follow-up vs baseline
- HbA1c significantly lower at follow-up vs baseline
- ∆−7 mmol/mol [∆−0.6%], p < 0.001
CGM metrics, matched cohorts
- rtCGM switch had significantly higher TIR 3.9-10.0 mmol/L and lower TAR >10.0 mmol/L, TBR <3.9 mmol/L and mean glucose vs isCGM
Hypoglycaemic events, body weight and insulin total daily dose (TDD), matched cohorts
- No significant differences between matched cohorts
Original publication
Effect of switching from intermittently scanned to real‐time continuous glucose monitoring on glycaemic outcomes in adults with type 1 diabetes: A real‐world, Canadian retrospective study. Diabet Med. Published 9 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →