Cognitive Function in Individuals with Chronic Hypoparathyroidism—A Prospective Observational Study
Main finding · Poorer with hypoparathyroidismResult — go to the resultF 8.65Authors' conclusion
This study provides evidence that cognitive dysfunction, particularly in attention and processing speed, is common in chronic hypoparathyroidism. Recognizing cognitive impairment in these patients is crucial, especially when discussing workability. Neuropsychological training as an adjunct therapy strategy may be beneficial in managing these cognitive deficits.
Study context
- Population
- Individuals with chronic hypoparathyroidism; 80.0% women, median age 44.5 ± 13.1, median disease duration 8.7 years (±5.3)
- Participants
- 30 vs 30
- Exposure
- Chronic hypoparathyroidism vs matched healthy controls
- Hypoparathyroidismn = 30
- Healthy controlsn = 30reference
- Outcome
- Cognitive performance in attention and processing speed
Methodological detailsmatched healthy control group, Tests: Trail Making Test A/B, Color-Word Interference Test, California Verbal Learning Test
- Matched healthy control group
- Tests: Trail Making Test A/B, Color-Word Interference Test, California Verbal Learning Test
Main finding
Poorer with hypoparathyroidism
F
8.65
P = 0.005*
As reported in the abstract
- Cognitive deficits in attention and processing speed: significantly higher percentage of patients vs controls
- 56.7% vs 3.3%
- Cognitive deficits in executive function: significantly higher percentage of patients vs controls
- 60.0% vs 16.7%
Observational data: associations, not effects.
Further findings
Cognitive deficits in attention and processing speed
- Significantly higher percentage of patients vs controls
- 56.7% vs 3.3%
Cognitive deficits in executive function
- Significantly higher percentage of patients vs controls
- 60.0% vs 16.7%
Original publication
Cognitive Function in Individuals with Chronic Hypoparathyroidism—A Prospective Observational Study. J Clin Endocrinol Metab. Published 15 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →