Diabetes technology

Clinical Outcomes with MiniMed TM 780G Advanced Hybrid Closed-Loop Therapy in 2- to 6-Year-Old Children with Type 1 Diabetes

Diabetes Technol TherPublished Pilot study

Authors' conclusion

AHCL is a feasible option for management of young children with type 1 diabetes.

Study context

Population
Children aged 2–7 years with T1D on insulin pump therapy; mean (SD) age 5.3 (0.8) years10 completed
Participants
11 children
Outcome
Continuous glucose monitoring (CGM) metrics
Methodological detailssingle-group, 2-week manual mode phase followed by 6-week advanced hybrid closed-loop (AHCL) phase
  • Single-group
  • 2-week manual mode phase followed by 6-week AHCL phase

Main finding

As reported in the abstract

CGM metrics in AHCL

Time in closed loop

96.7 (3.9)%

TIR, mean (SD)

72.6 (7.4)%

Time <70 mg/dL

3.0 (1.74)%

Time <54 mg/dL

0.63 (0.46)%

Original publication

Clinical Outcomes with MiniMed TM 780G Advanced Hybrid Closed-Loop Therapy in 2- to 6-Year-Old Children with Type 1 Diabetes. Diabetes Technol Ther. Published 8 March 2024. doi:10.1089/dia.2023.0508

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