Diabetes technology

Daytime hypoglycemic episodes during the use of an advanced hybrid closed loop system

Diabetes Res Clin PractPublished Retrospective observational study

Authors' conclusion

Our results confirmed the general improvement of glycemic outcomes obtained with the advanced hybrid closed loop system; however more hypoglycemic episodes during daytime were evident.

Study context

Population
Patients with T1D
Participants
30 vs 30
Exposure
AHCL vs PLGS sensor-augmented pump
  • Advanced hybrid closed loopn = 30
  • Predictive low glucose suspendn = 30reference
Outcome
Hypoglycemic risk
Follow-up
Three months

Main finding

As reported in the abstract

Hypoglycemia
  • No severe hypoglycemia occurred in either group
  • No differences in % time below 70 mg/dl and 54 mg/dl
  • More hypoglycemic episodes during daytime, but not nighttime, with advanced hybrid closed loop

Observational data: associations, not effects.

Further findings

Advanced hybrid closed loop reduced time above 180 mg/dL and increased TIR vs predictive low glucose suspend

Original publication

Daytime hypoglycemic episodes during the use of an advanced hybrid closed loop system. Diabetes Res Clin Pract. Published 11 November 2023. doi:10.1016/j.diabres.2023.111011

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