One-Year Follow-Up of Advanced Hybrid Closed-Loop System in Adults with Type 1 Diabetes Previously Naive to Diabetes Technology: The Effect of Switching to a Calibration-Free Sensor
Authors' conclusion
AHCL system in adults significantly improves glycemic outcomes. This improved glycemic control was maintained over the 12 months. Switching to a calibration-free sensor (G4S) did not affect outcomes but required less patient involvement.
Study context
- Population
- Adults with T1D previously naive to diabetes technology, switched from MDI + blood glucose meter to advanced hybrid closed-loop (AHCL)completed 1 year
- Participants
- 18 adults
- Exposure
- AHCL (MM 780G) after switching from MDI + blood glucose meter; switch to calibration-free sensor (G4S) at month 6
- MM 780Gn = 18
- Outcome
- TIR (70-180 mg/dL)
- Follow-up
- Over 12 months
Methodological detailssingle-group, 1-year follow-up
- Single-group
- 1-year follow-up
Main finding
As reported in the abstract
Time in range (TIR) remained stable; lowest month 9
83.2%
TIR highest month 3
84.8%
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| TIR 3 months before vs 3 months after switching to G4SNo difference | P = 0.614 |
Original publication
One-Year Follow-Up of Advanced Hybrid Closed-Loop System in Adults with Type 1 Diabetes Previously Naive to Diabetes Technology: The Effect of Switching to a Calibration-Free Sensor. Diabetes Technol Ther. Published 13 June 2023. doi:10.
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