Children and adolescent with suboptimal control of type 1 diabetes improve during the first 2 years on automated insulin delivery system
Authors' conclusion
Glycaemic control in patients not reaching treatment goals improved significantly after the initiation of the AID system, and the favourable effect lasted throughout the follow-up. AID treatment could be an option for also those paediatric patients with T1D who do not have good skills in diabetes management.
Study context
- Population
- Patients aged 7 to 16 years with T1D and haemoglobin A1C (HbA1c) above 53 mmol/mol/7.0% who initiated AID between 24 October 2020 and 5 January 2022, Helsinki University Hospital
- Participants
- 79 patients
- Exposure
- AID system, before vs after initiation
- AIDn = 79
- Outcome
- Glycaemic control: changes between 0 and 3 months
- Follow-up
- 0 to 3 months
Methodological detailssingle-group, single-centre
- Single-group
- Single-centre
Main finding
As reported in the abstract
Time in tight range (TITR) increase, mean (SD)
11.7%
10.6p < 0.001
Time in range (TIR) increase, mean (SD)
18.1%
13.7p < 0.001
HbA1c decrease
−8.3 mmol/mol [8.7]/−2.9% [2.9]
p < 0.001
Mean sensor glucose (SG) decrease
−1.8 mmol/L
1.7p < 0.001
Observational data: associations, not effects.
Further findings
Glycaemic control at 12 and 24 months
- Effects were sustainable and still visible at 12 and 24 months
Original publication
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