Pediatric endocrinology

Challenges in developing a quantitative method of measuring breast development using 3D imaging: An example of a novel method for use in induced breast development with exogenous oestrogen

Clin Endocrinol (Oxf)Published Prospective observational study

Authors' conclusion

3D imaging is a promising novel tool to provide quantitative breast volume assessment in individuals undergoing breast induction with exogenous oestradiol treatment.

Study context

Population
Single male subject for method development; females undergoing pubertal induction with exogenous oestradiol, Paediatric Gynaecology and Reproductive Endocrinology clinics, University College London Hospitalplus single male subject
Participants
29 participants
Outcome
Reproducibility and validity of 3D imaging for differential breast volume

Main finding

As reported in the abstract

Intraobserver reproducibility with static image manipulation (intraclass correlation (ICC))

0.77

Intraobserver reproducibility for breast volume in induced breast development (ICC)

0.99

Observational data: associations, not effects.

Original publication

Challenges in developing a quantitative method of measuring breast development using 3D imaging: An example of a novel method for use in induced breast development with exogenous oestrogen. Clin Endocrinol (Oxf). Published 28 August 2022. doi:10.1111/cen.14815

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