Cumulative BMI and incident prediabetes over 30 years of follow‐up: The CARDIA study
Main finding · Incident prediabetes by cBMI quartileResult — go to the resultHazard rate ratio 2.064 95% CI 1.793–2.377Authors' conclusion
The cumulative burden of higher weight and longer duration was associated with incident prediabetes, but this association was statistically significant only after a higher threshold was reached. Strategies for prevention of prediabetes in middle age may focus on avoiding overweight in young adulthood to limit duration.
Study context
- Population
- Black and White men and women aged 18 to 30 years in 1985 to 1986, free of prediabetes or diabetes at baseline (CARDIA study)
- Participants
- 4,190 participants
- Exposure
- Cumulative BMI quartiles
- Outcome
- Incident prediabetes
- Follow-up
- 30 years
Methodological detailsbiracial, observational, 30-year follow-up
- Biracial
- Observational
- 30-year follow-up
Main finding
Incident prediabetes by cumulative BMI (cBMI) quartile
Hazard rate ratio
2.064
95% CI 1.793–2.377
Q4vs Q1
hazard rate ratio 2.064 (95% CI 1.793–2.377)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Mean cBMI by prediabetes status
P < 0.0001
Incidence of prediabetes · 30 years
- Developed prediabetes
- 46.2%
Original publication
Cumulative BMI and incident prediabetes over 30 years of follow‐up: The CARDIA study. Obesity (Silver Spring). Published 15 September 2023. doi:10.
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