Can the postload-fasting glucose gap be used to determine risk of developing diabetes in chinese adults: A prospective cohort study
Authors' conclusion
The risk of developing prediabetes/diabetes after 3.2 years of follow-up was higher in the participants with high post load. It suggested that postload-fasting gap may be a simple tool to predict the risk of developing prediabetes, diabetes or reversal to NGT.
Study context
- Population
- Chinese adults without diabetes
- Participants
- 3,094 adults
- Exposure
- High post load vs low post load at baseline oral glucose tolerance test (OGTT)
- High post loadn = 2,392
- Low post loadn = 702reference
- Outcome
- Incidence of diabetes
- Follow-up
- Average of 3.2 years
Main finding
As reported in the abstract
- Overall developed diabetes
- 282 (9.1 %)
Observational data: associations, not effects.
Further findings
Incident prediabetes, per 1,000 person-years
Progression from prediabetes to diabetes, per 1,000 person-years
Reversal from prediabetes to NGT, per 1,000 person-years
| Outcome | High post load | Low post load |
|---|---|---|
| Mean postload-fasting gap · baseline | mean 1.8 ± 1.2 mmol/L | mean −0.8 ± 0.7 mmol/L |
Incident prediabetes, per 1,000 person-years
- HR significantly higher with high post load
Progression from prediabetes to diabetes, per 1,000 person-years
- HR significantly higher with high post load
Reversal from prediabetes to normal glucose tolerance (NGT), per 1,000 person-years
- HR lower with high post load
Original publication
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