Diabetes complications

Can diabetic peripheral neuropathy predict lacunar stroke in patients with diabetes?

Diabetes MetabPublished Retrospective observational study

Main finding · Small-vessel disease (SVD) stroke mechanismResult — go to the resultAdjusted odds ratio 5.08 CI 1.17–22.14

Authors' conclusion

These findings highlight a common pathophysiology between DPN and SVD.

Study context

Population
Patients hospitalised with ischemic stroke, Cayenne general hospital; mean age 64.14 ± 15.2 years, 62.4 % male5.8 % with diabetic peripheral neuropathy (DPN)
Participants
226 patients
Exposure
DPN vs no DPN
Outcome
Association between the mechanism of stroke and the presence of DPN
Methodological detailssingle-centre
  • Single-centre

Main finding

Small-vessel disease (SVD) stroke mechanism

Adjusted odds ratio

5.08

CI 1.17–22.14

DPNvs No DPN
aOR 5.08 (CI 1.17–22.14)

As reported in the abstract

Observational data: associations, not effects.

Original publication

Can diabetic peripheral neuropathy predict lacunar stroke in patients with diabetes? Diabetes Metab. Published 9 June 2025. doi:10.1016/j.diabet.2025.101675

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