Calcaneal quantitative ultrasound parameters strongly correlate with DXA measurements in patients with acromegaly
Authors' conclusion
cQUS parameters showed a good correlation with DXA evaluation in patients with acromegaly, comparable to the observation in the general population. cQUS-derived T-score can accurately discriminate osteopenia in patients with acromegaly.
Study context
- Population
- Patients with acromegaly and healthy controls undergoing DXA and calcaneal quantitative ultrasound (cQUS)
- Participants
- 56 vs 59
- Exposure
- Patients with acromegaly vs healthy controls: calcaneal quantitative ultrasound (cQUS) vs DXA
- AGn = 56
- CGn = 59reference
- Outcome
- Correlation of cQUS parameters with DXA-derived T-score
Methodological detailscontrols matched for age, sex and BMI
- Controls matched for age, sex and BMI
Main finding
As reported in the abstract
- All cQUS parameters showed a good correlation with DXA-derived T-score in both AG and CG
- p<0.001
Observational data: associations, not effects.
Further findings
| Outcome | AG | P value |
|---|---|---|
| cQUS-derived T-scoreNot significantly different | 0.40 (IQR −1.60–1.50) | P = 0.068 |
- Discriminatory ability of cQUS-derived T-score for osteopenia, AG vs CG · similar
- P = 0.325
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Calcaneal quantitative ultrasound parameters strongly correlate with DXA measurements in patients with acromegaly. Pituitary. Published 18 May 2026. doi:10.
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