Gestational diabetes & diabetes in pregnancy
Breastfeeding Intensity and Early Postpartum Lipid Profiles Among Women With Prior Gestational Diabetes
Authors' conclusion
This study found that HIB was associated with more favorable early postpartum lipid profiles after adjustment for insulin sensitivity among women with prior gestational diabetes
Study context
- Population
- Japanese women with prior GDM undergoing metabolic evaluation at 6 to 9 weeks post partum, tertiary medical center, December 1, 2014, to November 30, 2020; mean (SD) age 34.0 (4.8) years
- Participants
- 470 women
- Exposure
- High-intensity breastfeeding vs no high-intensity breastfeeding (HIB)
- HIBn = 369
- Outcome
- Fasting lipid profiles and dyslipidemia (Japan Atherosclerosis Society criteria)
- Follow-up
- 6 to 9 weeks post partum
Methodological detailssingle tertiary medical center
- Single tertiary medical center
Main finding
As reported in the abstract
TG
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | aOR (95% CI) | |
|---|---|---|
| HypertriglyceridemiaHIBvs No HIBAdjusted analysis | 0.25 (0.13–0.51) | |
| Elevated LDL-C to HDL-C ratioHIBvs No HIBAdjusted analysis | 0.27 (0.15–0.49) | |
| 0.10.31310Adjusted odds ratio (log scale) |
| Outcome | HIB | P value |
|---|---|---|
| HDL-CHIB vs No HIB | mean 73.9 (SD 17.8) mg/dL | P < 0.001 |
| LDL-C to HDL-C ratioHIB vs No HIB | mean 1.8 (SD 0.7) | P < 0.001 |
- High-density lipoprotein cholesterol (HDL-C): No HIB mean 63.0 (SD 14.0) mg/dL
- LDL-C to HDL-C ratio: No HIB mean 2.3 (SD 0.7)
Hypertriglyceridemia
- Association remained significant after adjustment for insulin sensitivity
Elevated LDL-C to HDL-C ratio
- Association remained significant after adjustment for insulin sensitivity
Original publication
Breastfeeding Intensity and Early Postpartum Lipid Profiles Among Women With Prior Gestational Diabetes. JAMA Netw Open. Published 3 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →