Body roundness index as a predictor of all-cause and cardiovascular mortality in patients with diabetes and prediabetes
Authors' conclusion
Our research indicates that among US adults with diabetes or prediabetes, BRI exhibits a U-shaped relationship with all-cause and cardiovascular mortality, with threshold values of 5.54 and 5.21, respectively.
Study context
- Population
- US adults with diabetes and prediabetes, National Health and Nutrition Examination Survey (NHANES) 2003–2018
- Participants
- 15,848 adults
- Exposure
- Body roundness index (BRI) and mortality
- Outcome
- All-cause mortality and cardiovascular mortality
- Follow-up
- Average 92.9 months
Methodological detailsNHANES 2003–2018, Cox proportional hazards model, restricted cubic splines
- NHANES 2003–2018
- Cox proportional hazards model
- Restricted cubic splines
Main finding
As reported in the abstract
- Died
- 2655 participants (12.73 %)
- Cardiovascular deaths
- 730 (3.44 %)
- U-shaped nonlinear association (restricted cubic splines (RCS)) of BRI with all-cause mortality; threshold
- 5.54
- U-shaped nonlinear association (RCS) of BRI with cardiovascular mortality; threshold
- 5.21
- BRI below threshold: all-cause mortality, HR
- 0.87 (0.81-0.93) (95% CI)
- BRI above threshold: all-cause mortality, HR
- 1.10 (1.06-1.14) (95% CI)
- BRI above threshold: cardiovascular mortality, HR
- 1.13 (1.07-1.20) (95% CI)
Observational data: associations, not effects.
Original publication
Body roundness index as a predictor of all-cause and cardiovascular mortality in patients with diabetes and prediabetes. Diabetes Res Clin Pract. Published 13 December 2024. doi:10.
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