Body mass index (BMI) associates with frequency of arterial hypertension and type 2 diabetes in obese patients candidates for bariatric surgery
Authors' conclusion
The frequency of AH and T2DM increases with increasing BMI levels. BMIQ outperforms BMI and obesity classes in modelling. This finding supports the use of fine stratification of BMI in clinical risk assessment. More specific studies are required to fully understand the impact of different BMI thresholds in determining the health status of obese patients, and to reduce the risks of BS in patients with extreme obesity.
Study context
- Population
- Patients with obesity (BMI ≥30.0 kg/m²) evaluated at presentation for bariatric surgery; 867 men and 2,619 women, aged 42.6 ± 11.48 years, mean BMI 41.9 ± 6.62 kg/m²
- Participants
- 3,486 patients
- Exposure
- BMI quartiles, BMI and obesity classes as predictors of Arterial Hypertension (AH), T2D and comorbidity score
- Outcome
- Frequency of AH, T2D and comorbidity score (AH + T2D) by BMI
Main finding
As reported in the abstract
- AH, T2D and CS frequency increased with increasing BMI quartiles
- p < 0.001
- AH, T2D and CS frequency increased with age
- p < 0.001
- Multivariable: age and BMI quartiles associated with AH
- p < 0.001
- Multivariable: age and BMI quartiles associated with T2D
- p < 0.001
- Multivariable: age and BMI quartiles associated with CS
- p < 0.001
Observational data: associations, not effects.
Original publication
Body mass index (BMI) associates with frequency of arterial hypertension and type 2 diabetes in obese patients candidates for bariatric surgery. Cardiovasc Diabetol. Published 24 November 2025. doi:10. 1186/ s12933-025-02989-x
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