Obesity

Body mass index (BMI) associates with frequency of arterial hypertension and type 2 diabetes in obese patients candidates for bariatric surgery

Cardiovasc DiabetolPublished Cross-sectional study

Authors' conclusion

The frequency of AH and T2DM increases with increasing BMI levels. BMIQ outperforms BMI and obesity classes in modelling. This finding supports the use of fine stratification of BMI in clinical risk assessment. More specific studies are required to fully understand the impact of different BMI thresholds in determining the health status of obese patients, and to reduce the risks of BS in patients with extreme obesity.

Study context

Population
Patients with obesity (BMI ≥30.0 kg/m²) evaluated at presentation for bariatric surgery; 867 men and 2,619 women, aged 42.6 ± 11.48 years, mean BMI 41.9 ± 6.62 kg/m²
Participants
3,486 patients
Exposure
BMI quartiles, BMI and obesity classes as predictors of Arterial Hypertension (AH), T2D and comorbidity score
Outcome
Frequency of AH, T2D and comorbidity score (AH + T2D) by BMI

Main finding

As reported in the abstract

AH, T2D and CS frequency increased with increasing BMI quartiles
p < 0.001
AH, T2D and CS frequency increased with age
p < 0.001
Multivariable: age and BMI quartiles associated with AH
p < 0.001
Multivariable: age and BMI quartiles associated with T2D
p < 0.001
Multivariable: age and BMI quartiles associated with CS
p < 0.001

Observational data: associations, not effects.

Original publication

Body mass index (BMI) associates with frequency of arterial hypertension and type 2 diabetes in obese patients candidates for bariatric surgery. Cardiovasc Diabetol. Published 24 November 2025. doi:10.1186/s12933-025-02989-x

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