Serum S100β and neuron-specific enolase correlate with obesity parameters in Mexican children
Authors' conclusion
S100β and NSE levels in blood were associated with indicators of metabolic impairment. Future studies are needed to determine if the increase of S100β and NSE in children with obesity is related to cognitive function.
Study context
- Population
- Mexican children aged 6–11 years with and without obesity
- Participants
- 80 children
- Exposure
- Children with obesity vs normal body weight
- Outcome
- Serum S100β and NSE levels
Main finding
As reported in the abstract
Serum S100β and NSE
- Children with obesity had ≈50% more circulating S100β and neuron-specific enolase (NSE)
Observational data: associations, not effects.
Further findings
Correlations with anthropometric and biochemical parameters
- Positive correlation between S100β and circulating resistin
- Positive correlation between NSE and BMI, waist circumference and waist-to-hip ratio
- Negative correlation between NSE and adiponectin
Original publication
Serum S100β and neuron-specific enolase correlate with obesity parameters in Mexican children. Int J Obes (Lond). Published 24 November 2025. doi:10.
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