Baseline and cumulative Chinese visceral adiposity index and diabetic kidney disease: A prospective cohort study
Authors' conclusion
Higher baseline and cumulative CVAI are associated with a higher risk of DKD. This finding suggests the health benefits of low levels of CVAI and the importance of its regular surveillance among individuals with diabetes.
Study context
- Population
- Patients with diabetes from the Kailuan study with complete repeated waist circumference, BMI, TG and HDL-C measurements
- Participants
- 7,874 patients
- Exposure
- High vs low baseline and cumulative Chinese visceral adiposity index
- Outcome
- Incident DKD (increased proteinuria or decreased estimated glomerular filtration rate (eGFR), preceded by diabetes)
Main finding
As reported in the abstract
Incident DKD
High CVAI vs Low CVAIHazard ratio (95% CI)
Baseline CVAI
1.24(1.09–1.42)
Cumulative CVAI
1.62(1.29–2.04)
- Positive association between Chinese visceral adiposity index (CVAI) level, baseline or cumulative, and diabetic kidney disease (DKD) incidence
- p for log-rank tests <0.001
Observational data: associations, not effects.
Further findings
Linearity of association of CVAI with incident DKD
- Baseline CVAI: linear positive association
- P-nonlinear = 0.264, p for overall <0.001
- Cumulative CVAI: linear positive association
- P-nonlinear = 0.765, p for overall <0.001
Original publication
Baseline and cumulative Chinese visceral adiposity index and diabetic kidney disease: A prospective cohort study. Diabetes Obes Metab. Published 15 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →