Autonomic function and hemodynamic changes in type 2 diabetes: insights into sympathetic activation and vascular stiffness
Authors' conclusion
While no direct correlation was found between arterial stiffness and autonomic function, increased sympathetic activation was linked to higher DBP. Early screening, lifestyle modifications, and targeted treatments could improve patient outcomes and T2D management.
Study context
- Population
- Patients with T2D
- Participants
- 81 patients
- Exposure
- T2D duration <10 years vs >10 years
- <10 yearsn = 50reference
- >10 yearsn = 31
- Outcome
- Relationship between autonomic function and vascular parameters
Main finding
As reported in the abstract
Sympathetic activity correlated with diastolic blood pressure (DBP) during wakefulness
r = 0.45
p = 0.003
Observational data: associations, not effects.
Further findings
Female participants
Comorbidities
- Albumin/creatinine ratio · significant albumin/creatinine ratio in the >10 years group
- P = 0.007
Albumin/creatinine ratio
- Biochemical differences were minimal
Original publication
Autonomic function and hemodynamic changes in type 2 diabetes: insights into sympathetic activation and vascular stiffness. Diabetes Res Clin Pract. Published 22 May 2025. doi:10.
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