Automated Insulin Delivery Systems Are Safe During Prolonged Religious Jewish Fasting Among Adolescents and Young Adults With Type 1 Diabetes
Authors' conclusion
Prolonged fasting appears to be safe for adolescents and young adults with type 1 diabetes using AID systems. However, individualized adjustments to system settings are often necessary to maintain glycemic stability during fasting. To our knowledge, this is the first report of the effects of using an AID system during Jewish religious fasting.
Study context
- Population
- Adolescents and young adults with T1D using automated insulin delivery (AID) systems during a 25-hour Jewish fast; mean age 17.4 ± 4.1 years, 47.5% male, diabetes duration 7.2 ± 4.3 years109 fasting days
- Participants
- 80 adolescents
- Outcome
- Outcomes of 25-hour fast
- Follow-up
- During the fast
Methodological detailsnon-interventional, Data collected on fast day, one week before and one week after
- Non-interventional
- Data collected on fast day, one week before and one week after
Main finding
As reported in the abstract
- Completed the fast without complications
- 71.5%
- Modified AID settings during fast (most commonly target glucose)
- 67.6%
- Mean blood glucose
- 135 ± 28.6 mg/dL
- TIR (70-180 mg/dL)
- 80.7%
- Time in hypoglycemia (<70 mg/dL)
- 2.6%
Observational data: associations, not effects.
Safety
Severe hypoglycemia or DKA · during or after the fast
- Cases of severe hypoglycemia or DKA
- 0
- Fasts primarily broken because of sensor-detected hypoglycemia
Original publication
Automated Insulin Delivery Systems Are Safe During Prolonged Religious Jewish Fasting Among Adolescents and Young Adults With Type 1 Diabetes. J Diabetes Sci Technol. Published 19 January 2026. doi:10.
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