Associations of Visceral Obesity Indices and Risk of Mild Cognitive Impairment in Patients With Diabetes: A Retrospective Cohort Study
Authors' conclusion
Higher visceral obesity indices were associated with an increased risk of MCI in patients with diabetes.
Study context
- Population
- Patients with diabetes, Nanjing Drum Tower Hospital; Mild Cognitive Impairment (MCI) per National Institute on Aging-Alzheimer's Association Workgroup criteria
- Participants
- 1,080 patients
- Exposure
- Visceral obesity indices for MCI risk
- Outcome
- MCI risk
Methodological detailsnomogram development, external validation in multicenter retrospective cohort and prospective cohort
- Nomogram development
- External validation in multicenter retrospective cohort and prospective cohort
Main finding
As reported in the abstract
Discrimination of MCI
| Group | AUC |
|---|---|
| Body roundness index (BRI) | 0.734 (95% CI 0.703-0.764) |
Body roundness index (BRI)
AUC0.734 (95% CI 0.703-0.764)
Observational data: associations, not effects.
Further findings
Nomogram (BRI, age, education, haemoglobin A1c (HbA1c)) discrimination, internal validation cohort
- AUC
- 0.804 (95% CI 0.777-0.830)
Nomogram discrimination, external validation Cohort 2 (multicenter retrospective)
- AUC
- 0.756 (95% CI 0.722-0.790)
Nomogram 10-year prediction, external validation Cohort 3 (prospective) · up to 10 years
- AUC
- 0.762 (95% CI 0.727-0.797)
Original publication
Associations of Visceral Obesity Indices and Risk of Mild Cognitive Impairment in Patients With Diabetes: A Retrospective Cohort Study. Diabetes Obes Metab. Published 6 May 2026. doi:10.
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