Associations of type 2 diabetes and the risk of migraine in Chinese populations
Main finding · Cumulative incidence of migraineResult — go to the resultHazard ratio 0.79 CI 0.65–0.95Authors' conclusion
This was the first study to validate that T2DM reduced the risk of migraine in a Chinese population cohort. Patients with migraine and T2DM may experience significant relief from their headache symptoms. Carrying out relevant mechanistic research may help to identify new targets for migraine treatment and contribute to further understanding the impact of T2DM or related metabolic disorders on an individual's health.
Study context
- Population
- Chinese population, China Health and Retirement Longitudinal Study (CHARLS); cross-sectional study of 168 migraine patients in Xiamen, ChinaCHARLS cohort
- Participants
- 9,873 participants
- Exposure
- T2D vs no T2D
- Outcome
- Incidence of migraine
- Follow-up
- 2015 to 2018
Methodological detailspopulation-based cohort (CHARLS), Cox proportional hazards model, multivariable linear regression
- Population-based cohort (CHARLS)
- Cox proportional hazards model
- Multivariable linear regression
Main finding
Cumulative incidence of migraine
Hazard ratio
0.79
CI 0.65–0.95
By group
T2DMvs Control
HR 0.79 (CI 0.65–0.95)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Migraine frequency and intensity (cross-sectional study, 168 migraine patients)
- Presence of T2DM significantly reduced migraine frequency and relieved migraine intensity
Original publication
Associations of type 2 diabetes and the risk of migraine in Chinese populations. Diabetes Metab. Published 23 January 2024. doi:10.
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