Lipids & metabolic liver disease
Associations of Sleep Health and Metabolic Syndrome Severity in Black Individuals: The Jackson Heart Sleep Study
An erratum to this article was published (J Clin Endocrinol Metab, 7 Aug 2025 ↗)
Authors' conclusion
Later sleep timing, irregular sleep duration, and poor sleep continuity were associated with more severe metabolic dysfunction in Black individuals, highlighting the importance of sleep health, beyond sleep duration, on metabolic health.
Study context
- Population
- Black individuals in the Jackson Heart Sleep Study (2012–2016); mean age 63 ± 11 years, 66% women, mean BMI 31.8 ± 6.8
- Participants
- 754 individuals
- Exposure
- Actigraphy sleep parameters vs odds of severe metabolic syndrome (MetS)
- Outcome
- Severe MetS: highest tertile of a validated sex-, race- and ethnicity-specific MetS severity Z score
Methodological detailscross-sectional analysis of the Jackson Heart Sleep Study (2012-2016), logistic regression, actigraphy
- Cross-sectional analysis of the Jackson Heart Sleep Study (2012-2016)
- Logistic regression
- Actigraphy
Main finding
As reported in the abstract
Each 1-hour later mid-sleep time: higher odds of severe MetS
14%
95% CI 1.01–1.30
Each 1-hour increase in sleep duration variability: higher odds of severe MetS
34%
95% CI 1.01–1.77
Each 1% decrease in sleep maintenance efficiency: higher odds of severe MetS
5%
95% CI 0.92–0.98
Each 1% increase in sleep fragmentation index: higher odds of severe MetS
2%
95% CI 1.01–1.04
Observational data: associations, not effects.
Further findings
Sleep characteristics
- Mean sleep onset (hh:mm)
- 23:10 ± 1:24
- Mean sleep duration
- 6.7 ± 1.1 hour
- Median sleep maintenance efficiency
- 88.9% (IQR, 85.7-91.5)
- Median sleep fragmentation index
- 28.3% (IQR, 23.2-34)
Original publication
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