Lipids & metabolic liver disease
Impact of physical activities in metabolic dysfunction associated steatotic liver disease, sarcopenia, and cardiovascular disease
Authors' conclusion
Regardless of types of exercise, physically active individuals had lower risks of MASLD, sarcopenia, and ASCVD.
Study context
- Population
- Participants of the Korean National Health and Nutrition Examination Surveys 2007–2020
- Participants
- 66,021 participants
- Exposure
- Physical activity (PA) types vs physical inactivity
- Outcome
- MASLD prevalence
Methodological detailsKorean National Health and Nutrition Examination Surveys 2007-2020
- Korean National Health and Nutrition Examination Surveys 2007-2020
Main finding
As reported in the abstract
- Prevalence of MASLD lower in all PA groups vs physically inactive
Observational data: associations, not effects.
Further findings
| Outcome | OR (95 % CI) | |
|---|---|---|
| ASCVD risk among individuals with MASLD (pooled ASCVD risk score)A-PAvs Physically inactive | 0.74 (0.73–0.75) | |
| ASCVD risk among individuals with MASLD (pooled ASCVD risk score)Multicomponent PAvs Physically inactive | 0.62 (0.61–0.64) | |
| Sarcopenia risk among individuals with MASLDA-PAvs Physically inactive | 0.77 (0.76–0.77) | |
| Sarcopenia risk among individuals with MASLDMS-PAvs Physically inactive | 0.97 (0.96–0.98) | |
| Sarcopenia risk among individuals with MASLDMulticomponent PAvs Physically inactive | 0.57 (0.57–0.58) | |
| 0.512Odds ratio (log scale) |
| Outcome | OR (95 % CI) |
|---|---|
| ASCVD risk among individuals with MASLD (pooled ASCVD risk score)Between MS-PA and Physically inactive · estimate outside printed interval | 0.70 (0.68–0.64) |
Atherosclerotic cardiovascular disease (ASCVD) risk among individuals with MASLD (pooled ASCVD risk score)
- Multicomponent PA associated with lower ASCVD risk vs other groups
Sarcopenia risk among individuals with MASLD
- Sarcopenia risk decreased among physically active individuals with MASLD
Original publication
Impact of physical activities in metabolic dysfunction associated steatotic liver disease, sarcopenia, and cardiovascular disease. Diabetes Res Clin Pract. Published 28 April 2025. doi:10.
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