Obesity

Associations of Body Mass Index Growth Rates and Body Composition With Cardiometabolic Risks in Chinese Preschool Children

J Clin Endocrinol MetabPublished Cohort study

Authors' conclusion

This study underscores the significant impact of BMI growth rates and body composition on cardiometabolic markers in 3-year-old children. The effects of BMI growth rates in specific periods varied by sex, birthweight, and size for gestational age, and boys exhibited a higher susceptibility to adverse outcomes.

Study context

Population
3-year-old Chinese preschool children; Body mass index (BMI) from 1 month to 3 years from medical records3,015 analysed
Participants
3,822 children
Outcome
BMI growth rates, body composition and cardiometabolic markers at 3 years
Follow-up
3 years
Methodological detailsPiecewise linear mixed models and logistic regression
  • Piecewise linear mixed models and logistic regression

Main finding

As reported in the abstract

Fat-free mass index negatively associated with high total cholesterol (TC) and non-HDL-C in boys and high low-density lipoprotein cholesterol (LDL-C) in girls
P < .05

Observational data: associations, not effects.

Original publication

Associations of Body Mass Index Growth Rates and Body Composition With Cardiometabolic Risks in Chinese Preschool Children. J Clin Endocrinol Metab. Published 12 August 2024. doi:10.1210/clinem/dgae544

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