Associations Between Patient‐Reported Outcomes and Glycaemic Exposure in Continuous Glucose Monitoring Users With Insulin‐Treated Diabetes Receiving Haemodialysis
Authors' conclusion
In individuals with insulin-treated diabetes receiving haemodialysis, CGM metrics were consistently associated with patient-reported experience, particularly thirst, and may provide clinically relevant insights beyond HbA1c.
Study context
- Population
- Adults with insulin-treated diabetes receiving haemodialysis and using continuous glucose monitoring (CGM)
- Participants
- 40 adults
- Outcome
- Key PROs (glucose monitoring satisfaction, diabetes distress, kidney failure-related symptom burden, thirst, hypoglycaemia awareness) and associations of CGM metrics and HbA1c with PROs
Main finding
As reported in the abstract
PROs and their associations with CGM metrics and HbA1c
- CGM satisfaction (median GMSS [IQR])
- 4.5 [3.9-4.7]
- Overall diabetes distress (median diabetes distress (DDS-17) [IQR])
- 1.7 [1.3-2.2]
- Problematic thirst
- 65%
- Higher TIR (3.9-10.0 mmol/L) and total GMSS score: B
- 0.009, p = 0.044
- Higher TIR and regimen-related distress: B
- - 0.012, p = 0.040
- Higher TIR and problematic thirst: OR per 5% increase
- 0.79, p = 0.021
- Higher TIR and intradialytic thirst: OR
- 0.77, p = 0.017
- Higher HbA1c and problematic thirst: OR per 11 mmol/mol increase
- 2.30, p = 0.014
- Higher HbA1c and nocturnal thirst: OR
- 1.66, p = 0.040
- Intact hypoglycaemia awareness
- 35/40, 87.5%
Observational data: associations, not effects.
Original publication
Associations Between Patient‐Reported Outcomes and Glycaemic Exposure in Continuous Glucose Monitoring Users With Insulin‐Treated Diabetes Receiving Haemodialysis. Diabetes Obes Metab. Published 8 June 2026. doi:10. 1111/ dom. 70954
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