Associations Between Patient‐Reported Outcomes and Glycaemic Exposure in Continuous Glucose Monitoring Users With Insulin‐Treated Diabetes Receiving Haemodialysis

Diabetes Obes MetabPublished Cross-sectional study

Authors' conclusion

In individuals with insulin-treated diabetes receiving haemodialysis, CGM metrics were consistently associated with patient-reported experience, particularly thirst, and may provide clinically relevant insights beyond HbA1c.

Study context

Population
Adults with insulin-treated diabetes receiving haemodialysis and using continuous glucose monitoring (CGM)
Participants
40 adults
Outcome
Key PROs (glucose monitoring satisfaction, diabetes distress, kidney failure-related symptom burden, thirst, hypoglycaemia awareness) and associations of CGM metrics and HbA1c with PROs

Main finding

As reported in the abstract

PROs and their associations with CGM metrics and HbA1c
CGM satisfaction (median GMSS [IQR])
4.5 [3.9-4.7]
Overall diabetes distress (median diabetes distress (DDS-17) [IQR])
1.7 [1.3-2.2]
Problematic thirst
65%
Higher TIR (3.9-10.0 mmol/L) and total GMSS score: B
0.009, p = 0.044
Higher TIR and regimen-related distress: B
- 0.012, p = 0.040
Higher TIR and problematic thirst: OR per 5% increase
0.79, p = 0.021
Higher TIR and intradialytic thirst: OR
0.77, p = 0.017
Higher HbA1c and problematic thirst: OR per 11 mmol/mol increase
2.30, p = 0.014
Higher HbA1c and nocturnal thirst: OR
1.66, p = 0.040
Intact hypoglycaemia awareness
35/40, 87.5%

Observational data: associations, not effects.

Original publication

Associations Between Patient‐Reported Outcomes and Glycaemic Exposure in Continuous Glucose Monitoring Users With Insulin‐Treated Diabetes Receiving Haemodialysis. Diabetes Obes Metab. Published 8 June 2026. doi:10.1111/dom.70954

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