Incidence and Associated Factors of Hypertension and Dyslipidemia Improvement in People With Type 2 Diabetes Remission: A Multicenter Real‐World Retrospective Cohort Study (JDDM84)
Study context
- Population
- People aged >18 years with T2D remission in a clinical database (JDDM84)complete-case dataset
- Participants
- 2,229 people
- Outcome
- Hypertension improvement (SBP <130 mmHg and DBP <80 mmHg without BP-lowering drugs) and dyslipidemia improvement (high-density lipoprotein cholesterol (HDL-C) ≥1.0 mmol/L and non-HDL-C <3.9 mmol/L without lipid-lowering drugs)
- Follow-up
- At the time of T2D remission
Methodological detailsmulticenter, real-world
- Multicenter
- Real-world
Main finding
As reported in the abstract
Improvement in hypertension and/or dyslipidemia
Improvement in people with either hypertension or dyslipidemia at baseline
≈25%
Improvement in people with both hypertension and dyslipidemia
79
8%
Observational data: associations, not effects.
Further findings
Baseline prevalence of comorbidities
- Hypertension
- 74%
- Dyslipidemia
- 62%
- Both
- 46%
Factors associated with improvement (logistic regression, multiple imputation dataset)
- Lower baseline BMI associated with hypertension improvement
- Higher baseline HbA1c associated with dyslipidemia improvement
- Younger age and ≥10% BMI reduction consistently associated with improvement in hypertension, dyslipidemia and both
Original publication
Incidence and Associated Factors of Hypertension and Dyslipidemia Improvement in People With Type 2 Diabetes Remission: A Multicenter Real‐World Retrospective Cohort Study (JDDM84). Diabetes Obes Metab. Published 8 June 2026. doi:10.
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