Association of stress hyperglycemia ratio with left ventricular function and microvascular obstruction in patients with ST-segment elevation myocardial infarction: a 3.0 T cardiac magnetic resonance study

Cardiovasc DiabetolPublished Cross-sectional study

Authors' conclusion

Fasting SHR in patients with ASTEMI successfully treated using PPCI is independently associated with impaired cardiac function and MVO. In patients with AMI and DM, fasting SHR is an independent determinant of the presence and extent of MVO.

Study context

Population
Consecutive patients with acute STEMI who underwent cardiac magnetic resonance (CMR) at index admission (3–7 days) after primary PCI
Participants
357 patients
Exposure
Fasting stress hyperglycemia ratio (SHR) tertiles
Outcome
Left ventricular function and global deformation, and MVO, by fasting SHR
Follow-up
3-7 days after PPCI
Methodological detailsconsecutive patients, CMR at index admission (3-7 days) after primary percutaneous coronary intervention (PPCI), fasting SHR tertiles
  • Consecutive patients
  • CMR at index admission (3-7 days) after PPCI
  • Fasting SHR tertiles

Main finding

As reported in the abstract

Spearman r, fasting SHR vs left ventricular ejection fraction (LVEF) (P<0.001)
- 0.252
Spearman r, fasting SHR vs left ventricular global function index (LVGFI) (P<0.001)
- 0.261
Spearman r, fasting SHR vs GRS (P<0.001)
- 0.245
Spearman r, fasting SHR vs GCS (P <0.001)
0.221
Spearman r, fasting SHR vs GLS (P <0.001)
0.249

Observational data: associations, not effects.

Further findings

After adjustment, fasting SHR associated with presence and extent of microvascular obstruction (MVO) in patients with acute myocardial infarction (AMI) and in those with AMI and diabetes mellitus (DM)

Original publication

Association of stress hyperglycemia ratio with left ventricular function and microvascular obstruction in patients with ST-segment elevation myocardial infarction: a 3.0 T cardiac magnetic resonance study. Cardiovasc Diabetol. Published 27 May 2024. doi:10.1186/s12933-024-02271-6

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