Association of stress hyperglycemia ratio with left ventricular function and microvascular obstruction in patients with ST-segment elevation myocardial infarction: a 3.0 T cardiac magnetic resonance study
Authors' conclusion
Fasting SHR in patients with ASTEMI successfully treated using PPCI is independently associated with impaired cardiac function and MVO. In patients with AMI and DM, fasting SHR is an independent determinant of the presence and extent of MVO.
Study context
- Population
- Consecutive patients with acute STEMI who underwent cardiac magnetic resonance (CMR) at index admission (3–7 days) after primary PCI
- Participants
- 357 patients
- Exposure
- Fasting stress hyperglycemia ratio (SHR) tertiles
- Outcome
- Left ventricular function and global deformation, and MVO, by fasting SHR
- Follow-up
- 3-7 days after PPCI
Methodological detailsconsecutive patients, CMR at index admission (3-7 days) after primary percutaneous coronary intervention (PPCI), fasting SHR tertiles
- Consecutive patients
- CMR at index admission (3-7 days) after PPCI
- Fasting SHR tertiles
Main finding
As reported in the abstract
- Spearman r, fasting SHR vs left ventricular ejection fraction (LVEF) (P<0.001)
- - 0.252
- Spearman r, fasting SHR vs left ventricular global function index (LVGFI) (P<0.001)
- - 0.261
- Spearman r, fasting SHR vs GRS (P<0.001)
- - 0.245
- Spearman r, fasting SHR vs GCS (P <0.001)
- 0.221
- Spearman r, fasting SHR vs GLS (P <0.001)
- 0.249
Observational data: associations, not effects.
Further findings
- After adjustment, fasting SHR associated with presence and extent of microvascular obstruction (MVO) in patients with acute myocardial infarction (AMI) and in those with AMI and diabetes mellitus (DM)
Original publication
Association of stress hyperglycemia ratio with left ventricular function and microvascular obstruction in patients with ST-segment elevation myocardial infarction: a 3.0 T cardiac magnetic resonance study. Cardiovasc Diabetol. Published 27 May 2024. doi:10. 1186/ s12933-024-02271-6
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