Type 1 diabetes

Association of type 1 diabetes mellitus and risk of atrial fibrillation: Systematic review and meta-analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis of cohort studies

Pooled result · AF riskResult — go to the resultHazard ratio 1.30 95% CI 1.15–1.47

Authors' conclusion

Our meta-analysis demonstrated that T1DM was an independent risk factor for AF development, but further studies should be performed to provide more convincing evidence.

Study context

Population
Cohort studies of T1D and atrial fibrillation (AF) incidence; databases searched to August 20224 cohort studies
Comparison
T1D vs control
Outcome
AF risk
Methodological detailsrandom-effects model
  • Random-effects model

Pooled result

As reported in the abstract

Hazard ratio

1.30

95% CI 1.15–1.47

T1Dvs Control
HR 1.30 (95% CI 1.15–1.47)

Further pooled results

OutcomeHR (95% CI)
AF incidence in femalevs male T1D patients (subgroup analysis)1.50 (1.26–1.79)

AF risk in T1D patients <65 vs over 65 years (subgroup analysis)

Increased AF risk in T1D patients <65 years compared with those over 65 years
HR = 1.45, 95%CI 1.21-1.74

Original publication

Association of type 1 diabetes mellitus and risk of atrial fibrillation: Systematic review and meta-analysis. Diabetes Res Clin Pract. Published 21 March 2023. doi:10.1016/j.diabres.2023.110629

Composed by AI from the published abstract and checked against it. How Briefs are made →

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