Association of type 1 diabetes mellitus and risk of atrial fibrillation: Systematic review and meta-analysis
Pooled result · AF riskResult — go to the resultHazard ratio 1.30 95% CI 1.15–1.47Authors' conclusion
Our meta-analysis demonstrated that T1DM was an independent risk factor for AF development, but further studies should be performed to provide more convincing evidence.
Study context
- Population
- Cohort studies of T1D and atrial fibrillation (AF) incidence; databases searched to August 20224 cohort studies
- Comparison
- T1D vs control
- Outcome
- AF risk
Methodological detailsrandom-effects model
- Random-effects model
Pooled result
As reported in the abstract
Hazard ratio
1.30
95% CI 1.15–1.47
T1Dvs Control
HR 1.30 (95% CI 1.15–1.47)
Further pooled results
| Outcome | HR (95% CI) | |
|---|---|---|
| AF incidence in femalevs male T1D patients (subgroup analysis) | 1.50 (1.26–1.79) | |
| 0.512Hazard ratio (log scale) |
AF risk in T1D patients <65 vs over 65 years (subgroup analysis)
- Increased AF risk in T1D patients <65 years compared with those over 65 years
- HR = 1.45, 95%CI 1.21-1.74
Original publication
Association of type 1 diabetes mellitus and risk of atrial fibrillation: Systematic review and meta-analysis. Diabetes Res Clin Pract. Published 21 March 2023. doi:10. 1016/ j. diabres. 2023. 110629
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