Association of stress hyperglycemia ratio and poor long-term prognosis in patients with myocardial infarction with non-obstructive coronary arteries
Main finding · MACEResult — go to the resultAdjusted hazard ratio 2.465 95% CI 1.461–4.159Authors' conclusion
Our data indicates, for the first time, that SHR is independently associated with poor long-term prognosis in patients suffering from MINOCA. The optimal SHR cut-off value for predicting clinical MACE among MINOCA patients was 0.86. These findings suggest that SHR may play a potential role in the cardiovascular risk stratification of the MINOCA population.
Study context
- Population
- Patients with myocardial infarction (MI) with non-obstructive coronary arteries (MI with non-obstructive coronary arteries (MINOCA))
- Participants
- 410 patients
- Exposure
- Stress hyperglycemia ratio (SHR) tertiles
- SHR1n = 143reference
- SHR2n = 131
- SHR3n = 136
- Outcome
- MACE
- Follow-up
- Mean 34 months
Main finding
As reported in the abstract
mean 34 months
Adjusted hazard ratio
2.465
95% CI 1.461–4.159
P = 0.001
By group
SHR3vs SHR1
aHR 2.465 (95% CI 1.461–4.159); P = 0.001
- Kaplan-Meier: SHR3 highest major adverse cardiovascular events (MACE) risk vs SHR1 and SHR2
- log-rank P < 0.001
Observational data: associations, not effects.
Further findings
MACE by SHR tertile and diabetes status
- SHR3 with diabetes had the highest hazard of MACE
- log-rank P < 0.001
Optimal SHR cut-off for predicting MACE (ROC)
- Optimal SHR cut-off
- 0.86
Original publication
Association of stress hyperglycemia ratio and poor long-term prognosis in patients with myocardial infarction with non-obstructive coronary arteries. Cardiovasc Diabetol. Published 16 January 2023. doi:10.
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